da vinci

Prostate Advances in Comparative Evidence (PACE)

This study is an international multicenter randomized study of organ confined low and intermediate risk prostate cancer and is composed of two parallel randomization schemes based on applicability of surgery as a treatment for the patient. Patients for whom surgery is a consideration are randomized to either laparoscopic or da Vinci prostatectomy or CyberKnife prostate SBRT(also known as CyberKnife radiosurgery). Patients for whom surgery is not a consideration are randomized to either conventionally fractionated radiation therapy or CyberKnife prostate SBRT. Efficacy, toxicity and quality of life outcomes will be compared across the pairs in each randomization.