30 Years of Evidence

Join the experts’ corner

Take a moment to explore a selection of publications and conference abstracts from around the globe. Find evidence for a wide range of treatment sites including malignant and benign disease, different fractionation schedules and real-time motion synchronization techniques for the CyberKnife® and Radixact®/ TomoTherapy® platforms. We update new papers on a regular basis. See how health professionals are helping to improve patient outcomes.

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Featured Case Studies

Tomotherapy/Radixact

Deep Inspiration Breath Hold Using VitalHold™ on the Radixact® System

A 45-year-old female patient was diagnosed with pT2N1M0 invasive ductal carcinoma of the left breast. The patient underwent breast conservation surgery with axillary dissection, followed by chemotherapy and radiation therapy. Radiation therapy was delivered by the Radixact® System, the latest generation of the TomoTherapy® Platform with surface guided radiotherapy (SGRT)

CyberKnife

Las Vegas CyberKnife® Experience with CyberKnife VOLO™ Optimization: Increase in Patient Throughput & Daily Volumes

Las Vegas CyberKnife worked with Accuray to upgrade their CyberKnife G4 version 9.6 and MultiPlan® version 4.5 to decrease treatment planning times significantly with new planning hardware and optimized software in the first release of Accuray Precision 1.0 and treatment delivery version 11.0.

CyberKnife

The CyberKnife® System Offers Alternative Treatment for Trigeminal Neuralgia

The Hôpital Notre-Dame du CHUM in Montreal, Canada, hosts a monthly clinic for patients with trigeminal neuralgia, a debilitating nerve disorder, that causes “electric” pain in the face. Eating, teeth brushing, shaving or simply a light gust of wind can trigger pain. In 2012, an 89-year-old male patient suffering from

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Publications
Selection of Conference Abstracts

Whole Body Irradiation with Intensity-Modulated Helical TomoTherapy Prior to Haematopoietic Stem Cell Transplantation: Analysis of Organs at Risk by Dose and its Effect on Blood Kinetics

Köksal M, Baumert J, Jazmati D, Schoroth F, Garbe S, Koch D, Scafa D, Sarria GR, Leitzen C, Massoth G, Delis A, Heine A, Holderried T, Brossart P, Müdder T, Schmeel LC | J Cancer Res Clin Oncol | 2023

Moderately Hypofractionated Helical TomoTherapy for Prostate Cancer: Ten-year Experience of a Mono-institutional Series of 415 Patients

Cozzi S, Ruggieri MP, Alì E, Ghersi SF, Vigo F, Augugliaro M, Giaccherini L, Iori F, Najafi M, Bardoscia L, Botti A, Trojani V, Ciammella P, Iotti C | In Vivo | 2023

Comparison of Clinical Outcomes Between Cone Beam CT-Guided Thermal Ablation and Helical TomoTherapy in Pulmonary Metastases from Hepatocellular Carcinoma

Wang F, Fan S, Shi Q, Zhao D, Sun H, Sothea Y, Wu M, Song H, Chen Y, Cheng J, Zeng Z, Yan Z, He J, Liu L | Front Oncol | 2023

Malignant Pleural Mesothelioma: Preliminary Toxicity Results of Adjuvant Radiotherapy Hypofractionation in a Prospective Trial (MESO-RT)

Parisi E, Arpa D, Ghigi G, Fabbri L, Foca F, Tontini L, Neri E, Pieri M, Cima S, Burgio MA, Belli ML, Luzzi L, Romeo A. | Cancers (Basel) | 2023

Hypofractionated Whole Breast Irradiation with Simultaneous Integrated Boost in Breast Cancer using Helical TomoTherapy with or Without Regional Nodal Irradiation: A Report of Acute Toxicities

Chitapanarux I, Nobnop W, Onchan W, Klunklin P, Nanna T, Sitathanee C, Kulpisitthicharoen S, Sripan P. | Front Oncol | 2023

Helical TomoTherapy of Lymph Node-negative Early-stage Breast Cancer After Breast-conserving Surgery: Long-term Results

Zwicker F, Klepper R, Hauswald H, Hoefel S, Raether L, Huber PE, Debus J, Schempp M. | Anticancer Res | 2023

Efficacy and Safety of a Treatment in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma (LANC) Involving Carotid Artery Invasion

Liu K, Wang Y, Ma L, Yang S, Zhang X | Eur Arch Otorhinolaryngol | 2023

Hypofractionated Stereotactic Irradiation for Optic Nerve Glioma

Zagirov RI, Trunin YY, Serova NK, Pronin IN, Antipina NA, Golanov AV | Zh Vopr Neirokhir Im | 2022

Every Other Day Stereotactic Radiation Therapy for the Treatment of Uveal Melanoma Decreases Toxicity

Yazici G, Kiratli H, Ozyigit G, Sari SY, Elmali A, Yilmaz MT, Koc I, Deliktas O, Gumeler E, Cengiz M, Zorlu F. | Radiother Oncol | 2022

Robotic CyberKnife Radiosurgery for the Treatment of Choroidal and Ciliary Body Melanoma

Liegl R, Schmelter V, Fuerweger C, Ehret F, Priglinger S, Muacevic A, Foerster P | AM J Opthalmol | 2023

The Impact of Robotic Fractionated Radiotherapy for Benign Tumors of Parasellar Region on the Eye Structure and Function

Orski M, Tarnawski R, Wylęgała E, Tarnawska D | J Clin Med | 2023

Risk-adapted Stereotactic Body Radiotherapy for Patients with Cervical Spinal Metastases

Wang HH, Tian SS, Yang JM, Sun BS, Chen Y, Song YC, Dong Y, Wang JS, Yuan ZY, Cui YL, Meng MB | Cancer Sci | 2022

Conventionally Fractionated Radiotherapy Versus CyberKnife Hypofractionated Radiotherapy for Painful Vertebral Haemangiomas – A Randomized Clinical Trial

Miszczyk M, Napieralska A, Woźniak G, Kraszkiewicz M, Gola M, Kalemba M, Głowacki G, Tomasik B, Kocot-Kępska M, Miszczyk L. | Radiother Oncol | 2022

Image-guided Robotic Radiosurgery for the Treatment of Arteriovenous Malformations

Loebel F, Pontoriero A, Kluge A, Iatì G, Acker G, Kufeld M, Cacciola A, Pergolizzi S, Vinci S, Lillo S, Xu R, Stromberger C, Budach V, Vajkoczy P, Senger C, Conti A. | PLoS One | 2022